Aspirin have the risk of stomach bleeding


Aspirin have the risk of stomach bleeding

Aspirin also known as acetylsalicylic acid. This is a drug used as analgesic (to relieve minor aches and pains)  antipathetic  (to reduce fever), and anti-inflammatory medication. According to studies low doses of Aspirin will reduce the risk of heart attack, means this have protective effects against cardiovascular disease, and it will reduce the chance of stroke.
But there is a big risk, some times there is chance for gastric bleeding, in case aspirin is combined with other medications that increase the risk of stomach bleeding.
Dr Rodríguez, of the Spanish Centre for Pharmacoepidemiological Research in Madrid, and his colleagues analysed a database of primary care patients in the UK. They identified 2,049 people ages 40 to 84 with gastric bleeding between 2000 and 2007, and 20,000 age- and gender-matched controls.
The researchers compared records of these two groups to find out what medications individuals were currently taking and what they had been prescribed over the past year.
About 31% of people with gastric bleeding episodes were taking low-dose aspirin, compared to 19% of controls.

What is the risks

People taking any daily dose of aspirin were at almost twice the risk of gastric bleeding than people not taking aspirin. People taking both aspirin and clopidogrel were three to four times more likely to have a stomach bleed than those taking neither drug.
Patients who were taking aspirin in addition to a range of other drugs, including anti-inflammatory drugs such as ibuprofen and anticoagulants such as warfarin had a higher bleeding risk than those taking just aspirin. aspirin will probably double the risk of major bleeding, and most of the major bleeding that occurs is attributed to gastrointestinal bleeding.”

How to protect patients from this risk.

Prescribe the medicines like proton pump inhibiter’s (PPIs) with aspirin. This will reduce the risk in some levels. Take care while taking the aspirin with out doctors prescription. If the patient have any history of gastrointestinal bleeding, peptic ulcer avoid taking aspirin.

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